Dosing chart / Sexual & hormonal
PT-141 vs Melanotan II
Dose, schedule, route and approval status side by side.
Reference only, not medical advice. Doses marked FDA-approved come from the US prescribing label. Doses marked Not approved are ranges reported from small studies or community use and have not been established as safe or effective in humans. Check anything here with a licensed clinician before acting on it. Read the full disclaimer.
| PT-141 | Melanotan II | |
|---|---|---|
| Status | FDA-approved | Not approved |
| Also known as | bremelanotide, Vyleesi | MT-2 |
| Typical dose | 1.75 mg | 250–500 mcg |
| How often | As needed | Daily, then 1–2 times weekly |
| Schedule | As needed, at least 45 minutes before sex. No more than one dose in 24 hours or eight a month. | Daily until tanned, then once or twice a week, as reported. |
| Daily equivalent | Not a daily drug | 250–500 mcg/day |
| Route | Subcutaneous | Subcutaneous |
| Duration | As needed | 2–4 week loading reported |
| Notes | Approved for low sexual desire in premenopausal women. Nausea is common, and it briefly raises blood pressure. Calculator values assume a compounded vial; the brand is an autoinjector. | Regulators in several countries, including the FDA, have warned against it. Reported effects include nausea, new or darkening moles, and prolonged erections. |
This page sets the two chart entries next to each other. It does not say which is better or whether either is right for you. Read member experiences on the PT-141 and Melanotan II pages.
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