Dosing chart / Longevity & immune
MOTS-c vs NAD+
Dose, schedule, route and approval status side by side.
Reference only, not medical advice. Doses marked FDA-approved come from the US prescribing label. Doses marked Not approved are ranges reported from small studies or community use and have not been established as safe or effective in humans. Check anything here with a licensed clinician before acting on it. Read the full disclaimer.
| MOTS-c | NAD+ | |
|---|---|---|
| Status | Not approved | Not approved |
| Also known as | – | nicotinamide adenine dinucleotide |
| Typical dose | 5–10 mg | 50–200 mg |
| How often | 2–3 times weekly | Daily to 2–3 times weekly |
| Schedule | Two or three times a week. | Daily to a few times a week, as reported. |
| Daily equivalent | ≈ 1.4–4.3 mg/day | up to 200 mg/day |
| Route | Subcutaneous | Subcutaneous |
| Duration | 4–8 weeks reported | Varies |
| Notes | Mitochondria-derived peptide studied mainly in mice. Doses are community-reported. | Not a peptide: a coenzyme that often appears on peptide lists. Injections commonly cause flushing and nausea. |
This page sets the two chart entries next to each other. It does not say which is better or whether either is right for you. Read member experiences on the MOTS-c and NAD+ pages.
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