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Dosing chart / Sexual & hormonal

Melanotan II vs Melanotan I

Dose, schedule, route and approval status side by side.

Reference only, not medical advice. Doses marked FDA-approved come from the US prescribing label. Doses marked Not approved are ranges reported from small studies or community use and have not been established as safe or effective in humans. Check anything here with a licensed clinician before acting on it. Read the full disclaimer.

Melanotan IIMelanotan I
StatusNot approvedFDA-approved
Also known asMT-2afamelanotide, Scenesse
Typical dose250–500 mcg16 mg implant
How oftenDaily, then 1–2 times weeklyEvery 2 months
ScheduleDaily until tanned, then once or twice a week, as reported.One implant under the skin every 2 months, placed by a clinician.
Daily equivalent250–500 mcg/day≈ 0.27 mg/day
RouteSubcutaneousSubcutaneous implant
Duration2–4 week loading reportedOngoing
NotesRegulators in several countries, including the FDA, have warned against it. Reported effects include nausea, new or darkening moles, and prolonged erections.Approved only as an implant for the light-sensitivity disorder erythropoietic protoporphyria. Injectable versions sold for tanning are unapproved; 0.5–1 mg daily is community-reported.

This page sets the two chart entries next to each other. It does not say which is better or whether either is right for you. Read member experiences on the Melanotan II and Melanotan I pages.

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