Ipamorelin vs Sermorelin

Dose, schedule, route and approval status side by side.

Reference only, not medical advice. Doses marked FDA-approved come from the US prescribing label. Doses marked Not approved are ranges reported from small studies or community use and have not been established as safe or effective in humans. Check anything here with a licensed clinician before acting on it. Read the full disclaimer.

	Ipamorelin	Sermorelin
Status	Not approved	Not approved
Also known as	–	Geref
Typical dose	100–300 mcg	200–500 mcg
How often	Daily, 1–3 times	Daily, at bedtime
Schedule	One to three times daily, commonly before bed.	Once daily at bedtime.
Daily equivalent	100–900 mcg/day	200–500 mcg/day
Route	Subcutaneous	Subcutaneous
Duration	8–12 weeks reported	3–6 months reported
Notes	Growth hormone secretagogue. Reached Phase 2 for post-surgical bowel recovery but was not approved.	Formerly FDA-approved for childhood growth hormone deficiency; the brand was discontinued commercially. Now available only through compounding.

This page sets the two chart entries next to each other. It does not say which is better or whether either is right for you. Read member experiences on the Ipamorelin and Sermorelin pages.

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